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The Role of microRNA-2911 in control of viral infections
Abstract
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in different mechanisms of gene regulation. Honeysuckle decoction (HD) extract has miRNA-2911 (miR-2911) and may be absorbed into the gastrointestinal (GI) system via SID transmembrane family member 1 (SIDT1) receptors. Several studies have shown inhibitory effects of miR-2911 on NA, PB2, and NS1 proteins of influenza virus (flu), VP1 of enterovirus 71 (EV71), IE62 of varicella-zoster virus (VZV), and SARS-COV-2 (SCOV-2) proliferation. MiRNA-2911 has the potential to change how these viruses are treated and controlled by employing herbal substances instead of chemical medications. This could be a new step in controlling viral infections but requires further studies.
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