The causative agents of malignant otitis externa among the patients referred to Ayatollah Rohani Hospital in Babol, Northern of Iran

Sadaf Salamatpour; Mohsen Karami; Keyvan Kiakojuri; Ahmad Reza Aminian; Saeid Mahdavi Omran; Mahdi Rajabnia; Abazar Pournajaf; Jalal Jafarzadeh; Akbar Hosseinnejad; Aliakbar Rajabzadeh; Mojtaba Taghizadeh Armaki

doi:10.61186/jcbior.4.1.191

Authors

Sadaf Salamatpour Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Mohsen Karami Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Keyvan Kiakojuri Department of Ear, Nose, and Throat, Faculty of Medicine, Roohani Hospital, Babol University of Medical Sciences, Babol, Iran
Ahmad Reza Aminian Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Saeid Mahdavi Omran Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Mahdi Rajabnia Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Abazar Pournajaf Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Jalal Jafarzadeh Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Akbar Hosseinnejad Department of Medical Mycology, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
Aliakbar Rajabzadeh Department of Anatomical Sciences, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Mojtaba Taghizadeh Armaki Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran https://orcid.org/0000-0003-1811-5829

DOI:

https://doi.org/10.61186/jcbior.4.1.191

Keywords:

Malignant, Otitis externa, Bacterial agents, Diabetes

Abstract

Malignant otitis externa is an invasive, inflammatory and necrotic form of the external ear canal. The aims of the present study was to determination of causative agents of malignant otitis externa. In a cross-sectional study, 112 patients with otitis externa referred to Ayatolallah Rohani hospital in Babol city from 2020-2021 entered the study. The diagnosis of the malignant otitis externa was based on clinical findings and the cause of the disease was based on laboratory finding. The diagnosis criteria were mainly clinical, which was the presence of necrotic tissue in the canal floor and histopathological findings. The demographic information of the studied patients, 48 cases (55.8%) were less than 41 years old, 52 cases (60.5%) were women, and 62 cases (72.1%) had diabetes. Out of 112 patients, 86 patients had otitis externa, and malignant infection was observed in 4 patients (4.7%) by bacterial culture. Also, 26 cases were excluded from the study due to fungal infection with filamentous and yeast causative agents. Out of 4 patients with malignant otitis externa, 3 had diabetes. According to the results of present study, the frequency of malignant otitis externa was less than 5%, and the high-risk groups for malignant otitis externa were women, and diabetic patients. Early diagnosis and treatment play a very important role in preventing complications disease and reducing the hospitalization.

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